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Process Engineer

Location: Pleasanton CA

10x Genomics is building tools for scientific discovery that reveal and address the true complexities of biology and disease. Through a combination of novel microfluidics, chemistry and bioinformatics, our award-winning Chromium™ System is enabling researchers around the world to more fully understand the fundamentals of biology at unprecedented resolution and scale. Learn more at 10xGenomics.com.

#GOEXPONENTIAL

Fueled by equal parts scientific vision and determined passion, we are delivering unprecedented innovation to short-read sequencing technologies and transforming how genomic information is accessed. You will feel the 10x difference the moment you enter our offices and labs. There’s a dynamic energy here, and we’re looking for the best of the best to be a part of it. We are seeking talented professionals excited to build new technology that advances scientific research while growing their career within a dynamic, supportive environment.

Process Engineer

10x is looking for an outstanding Process Engineer to join the Process Development team. This is a key position for the commercialization of consumable products associated with Next Generation Sequencing chemistries.  This person will be responsible for developing and integrating process control and yield optimization solutions for complex reagent manufacturing workflows and identifying process to function relationships.

The ideal candidate will have a strong background in statistics and data analysis.  Knowledge and hands on experience with trend analysis, yield enhancement methods, correlation and ANOVA analysis, quality systems databases, developing statistical process control for reagent manufacturing and previous experience in manufacturing SPC are required.

Individuals applying for this position must be self-starters, strategic thinkers, action driven, flexible in changing direction and methods, thrive in a fast-paced environment, excel at managing multiple priorities, succeed in communicating with all levels within the organization and provide immediate contribution.

Key Responsibilities

  • Develop and implement process monitoring for robust manufacturing of complex reagents. 
  • Establish requirements for MES system 
  • Write custom database queries to extract and aggregate MES, SCADA, and QC data from multiple databases, analyze this data and establish trends and guard bands for process control. 
  • Identify key parameters and establish statistically relevant correlations between regent QC metrics and next generation sequencing metrics. 
  • Contribute to CAPA investigations and remediation.  Provide data analysis and support for root cause investigations.  
  • Provide guidance for expansion of data collection activities to R&D organization.  Develop light weight sample tracking and automated data collection for subsequent sequencing. 
  • Produce reports on process / method capabilities, component variability and ANOVA. 
  • Maintain accurate and detailed records of testing, conduct in-depth data analysis, and clearly communicate these results through documentation and presentations.  

Required Skills and Background 

 

  • Advanced degree in Statistics, Process Chemistry, Chemical or Manufacturing Engineering or related field, with an emphasis in statistical process control and monitoring. 
  • BS with 5+ years of experience, or MS / PhD with 1-3 years of experience. 
  • Relevant experience developing process control for the manufacture of successful products. 
  • Previous experience programming databases is required.  Experience with Oracle, Ignition, Postgres databases and NetSuite Advanced Manufacturing highly desired. 
  • Ability to work with scientist and engineers to establish correlations between QC data and sequencing metrics.  Ability to identify potential sources of root cause for failure analysis. 
  • Familiar with Illumina Next Gen Sequencing data and key sequencing pipelines and metrics. 
  • Experience with standard statistical analysis software (e.g. JMP, CHARTrunner, Minitab, Matlab) is required. 
  • Desire to be part of a rapidly evolving organization, with a compelling technology, and taking products and processes to the next level.

 

All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, sexual orientation, gender identity, national origin, protected veteran status, or on the basis of disability.

 

 

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Pleasanton, CA

10x Genomics
6230 Stoneridge Mall Road
Pleasanton, CA 94588-3260
+1 925 401 7300
+1 800 709 1208

San Francisco, CA

10x Genomics
160 Spear St.,
Suite 1130
San Francisco, CA 94105
+1 925 401 7300
+1 800 709 1208

Leiden, The Netherlands

10x Genomics B.V.
Crown Business Center Key Point II,
Schipholweg 103,
2316 XC Leiden,
The Netherlands

Stockholm, Sweden

Spatial Transcriptomics,
Part of 10x Genomics, Inc
Södra Fiskartorpsvägen 15C,
114 33 Stockholm,
Sweden

Singapore

10x Genomics Pte Ltd
Science Park 2,
20 Science Park Road,
#02-32A/33 Teletech Park,
Singapore 117674

Shanghai, China

10x Genomics (Shanghai) Co., Ltd
2421, Cloud 9 International Plaza,
No 1018 Changning Road,
Shanghai, 200042 China